Table 1 Bonferroni associations in candidate gene meta-analyses

From: The schizophrenia genetics knowledgebase: a comprehensive update of findings from candidate gene studies

SNP

Gene

Chr

Position

Reference allele

Population

Cases vs controls (studies included)

P-valuea

OR (95% CI)b

I 2

PGC (p)

PGC (odds ratio)

rs1801133

MTHFR

1

11856378

T

All populations

14242 vs 18541 (45)

2.61E-05c

1.12 (1.06–1.18)

57

0.55

1.0068

rs910694

PDE4B

1

66795976

C

All populations

1523 vs 1258 (4)

1.05E-05

0.77 (0.68–0.86)

2

0.48

0.99

rs1344706

ZNF804A

2

185778428

G

All populations

19724 vs 22368 (33)

1.72E-05c

0.92 (0.89–0.96)

31

1.27E-10

0.93

rs11098403

TRAM1L1/NDST3

4

118646907

G

Asian

1861 vs 2081 (4)

1.45E-10

0.65 (0.58–0.75)

0

3.52E-05

1.05

rs6932590

PRSS16/POM121L2

6

27248931

C

All populations

8351 vs 15485 (15)

3.05E-07c

0.86 (0.81–0.91)

0

1.02E-20

0.89

rs13211507

PGBD1

6

28257377

C

Caucasian

4914 vs 12522 (13)

1.47E-06

0.76 (0.68–0.85)

7

6.28E-26

0.81

rs2071287

NOTCH4

6

32170433

A

Asian

6608 vs 12918 (6)

4.38E-05

0.89 (0.85–0.94)

14

N.A

N.A

rs3131296

NOTCH4

6

32172993

A

All populations

6112 vs 13633 (15)

2.22E-07c

0.79 (0.73–0.87)

0

N.A

N.A

rs1006737

CACNA1C

12

2345295

A

All populations

14337 vs 15969 (9)

5.61E-07c

1.18 (1.1–1.25)

0

1.09E-16

1.1

rs778293

DAOA/-

13

106169199

G

Asian

2899 vs 3218 (4)

1.60E-05

1.18 (1.09–1.27)

0

0.53

0.99

rs165815

ARVCF

22

19959473

C

All populations

2982 vs 3253 (6)

6.36E-07c

1.64 (1.35–1.99)

0

0.04

0.97

  1. The table presents Bonferroni-significant polymorphisms in Asians and/or Caucasians after adjusting for publication bias and sensitivity analyses
  2. aThe p value and odds ratio were calculated based on random-effect model
  3. bOdds ratio was calculated under allelic model corresponding to the reference allele
  4. cWe present the results (p-value and odds ratio) in sensitivity analysis for the polymorphism
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