Fig. 3: Effects of spermine and pH on homomeric GluR3. | Translational Psychiatry

Fig. 3: Effects of spermine and pH on homomeric GluR3.

From: Electrophysiological evaluation of extracellular spermine and alkaline pH on synaptic human GABAA receptors

Fig. 3

a Ion currents elicited with 100 mM kainate were inhibited by spermine with pH adjusted to 7.36 by 51 ± 2.5% (n = 6). b Perfusion of extracellular solution with pH adjusted to 6 inhibited kainate currents to 89 ± 7.2% of the control and pH adjusted to 10 increased it to 114 ± 5.8 % (n = 5; p < 0.01 paired, two-sided t Student’s test)

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