Fig. 4: TALLYHO/JngJ mice show changes in cerebellar and plasma Insulin-like growth factor 1 protein levels.
From: Converging evidence points towards a role of insulin signaling in regulating compulsive behavior
a The concentration of Insulin-like growth factor 1 (Igf1) is reduced in the cerebellum of TALLYHO/JngJ (TH) mice compared with their controls, SWR/J mice (90.2 ± 12.3 vs. 168.7 ± 15.5 pg/ml, n = 6 [TH] and n = 8 [SWR/J], p = 0.0002). b Interestingly, the concentration of Igf1 is increased in the blood plasma of TH mice (1217.4 ± 453.6 vs. 97.6 ± 22.2 pg/ml, n = 7 [TH] and n = 4 [SWR/J], p = 0.049)
