Fig. 3: A sncRNA signature to predict conversion of MCI patients.
From: A combined miRNA–piRNA signature to detect Alzheimer’s disease
a Demographic information of the DCN longitudinal and multicenter cohort of MCI. In total, baseline CSF exosomes from 17 participants diagnosed with MCI were analyzed. At the 10-year follow-up six individuals had converted to dementia (3 male and 3 female). b ROC shows performance of our three piRNA signatures (identified in the signature cohort) on the DCN cohort consisting of converting and stable MCI participants. c ROC with the mean AUC of 0.96 was obtained by using a combination of our piRNA signature with pTau and Aβ42/40 ratio values. Error bars indicate SD
