Fig. 2

Scatterplot showing the relationship between the optimal (p-value threshold = 5 × 10-8 [left] and 0.05 [right]) radial glia cells-like polygenic score (PRSRad; x-axis, standardized) and the change from baseline (V1) in the volume of the left and right hippocampal subfields CA4/dentate gyrus after 3 months of aerobic exercise (V3) (y-axis, corrected residuals). Positive values in the y-axis indicate a gain in volume after 3 months; and positive values in the x-axis, a higher genetic risk burden. Also shown are regression line and 95% confidence intervals based on the predicted means from the regression line