Fig. 4: Effects of D4R expression and dopamine on global DNA methylation in D4R-transfected CHO cells.
From: Methylation-related metabolic effects of D4 dopamine receptor expression and activation
Global DNA methylation was measured in wild-type (WT) CHO cells or CHO cells transfected with D4.2R, D4.4R, or D4.7R. Cells were untreated (C) or treated for 8 h with either dopamine (D; 10 µM) or the D4-selective antagonist L-745870 (L; 100 nM) or both (DL) (n = 6). Asterisks indicate significant differences from matched WT group (***p < 0.01). ^ indicates significant difference from untreated control group (C) (^p < 0.05)
