Table 1 Set of 58 genes selected for targeted analysis.
From: Mutations in sphingolipid metabolism genes are associated with ADHD
Enzyme | Gene | Previous association with ADHD (ref.) |
|---|---|---|
Serine-palmitoyl transferase | SPTLC1 | |
SPTLC2 | ||
SPTLC3 | ||
SPTSSA | ||
SPTSSB | Association with gene-related CNV69 | |
3-Ketodihydrosphingosine reductase | KDSR | |
Ceramide synthase | CERS1 | |
CERS2 | ||
CERS3 | ||
CERS4 | ||
CERS5 | ||
CERS6 | ||
Dihydroceramide desaturase | DEGS1 | |
DEGS2 | ||
Fatty acid elongases | ELOVL1 | |
ELOVL2 | ||
ELOVL3 | ||
ELOVL4 | ||
ELOVL5 | ||
ELOVL6 | Trend associated SNP66 | |
ELOVL7 | Gene-related CNV65 | |
Ceramide kinase | CERK | |
Sphingomyelin synthase | SMS1 | |
SMS2 | ||
Sphingomyelinase | SMPD1 | Gene-related CNV69 |
SMPD2 | ||
SMPD3 | ||
SMPD4 | Association with gene-related region68 | |
SMPDL3A | Association with gene-related region67 | |
SMPDL3B | ||
ENPP7 | ||
UDP-glucose ceramide glucosyltransferase | UGCG | Association with gene-related region67 |
UDP-galactosyltransferase 8 | UGT8 | |
Galactosylceramidase | GALC | |
Beta-1-4-galactosyltransferase 6 | B4GALT6 | Association with gene-related region67 |
Galactose-3-O-sulfotransferase | GAL3ST1 | |
Alkaline ceramidase | ACER1 | |
ACER2 | ||
ACER3 | ||
Acid ceramidase | ASAH1 | |
ASAH2 | ||
Sphingosine kinase | SPHK1 | |
SPHK2 | ||
S1P-phosphatase | SGPP1 | |
SGPP2 | ||
S1P lyase | SGPL1 | |
S1P-receptor | S1PR1 | |
S1PR2 | ||
S1PR3 | ||
S1PR4 | ||
S1PR5 | ||
Fatty acid desaturase | FADS1 | |
FADS2 | ||
FADS3 | ||
N-SMase activation associated factor | NSMAF | |
Ceramide transfer protein | COL4A3BP |
