Table 3 Results for replication in the Paisa and US cohorts using FBATs.

From: Mutations in sphingolipid metabolism genes are associated with ADHD

Cohort

Chr

SNP

Position

Gene

Allele

Freqa

HGVS Cod/Prot

PFBAT

Paisa

14

rs398607

88,407,888

GALC

G

0.38

c.1685T > C/p.Ile562Thr

4.0 × 10−2

 

11

rs7951904

6,412,931

SMPD1

G

0.1

c.636T > C/p.Asp212Asp

7.2 × 10−2

 

2

rs13393173

169,389,091

CERS6

A

0.16

c.171 − 15015G > A/intronic variant

9.9 × 10−2

US

2

rs4668077

169,439,848

CERS6

A

0.18

c.407 + 22016A > G/intronic variant

1.1 × 10−2

 

14

rs1805078

88,450,770

GALC

A

0.058

c.550C > T/p.Arg184Cys

3.9 × 10−2

 

2

rs13393173

169,389,091

CERS6

A

0.22

c.171 − 15015G > A/intronic variant

4.4 × 10−2

 

11

rs7951904

6,412,931

SMPD1

G

0.13

c.636T > C/p.Asp212Asp

7.9 × 10−2

  1. Chr chromosome, SNP single-nucleotide polymorphism, CR call rate, P FBAT-based P value, FDR false discovery rate, HGVS Human Genome Variation Society, FBAT family-based association test.
  2. aAs estimated in these cohorts.
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