Table 1 Statistical summary of GWAS and MTAG results.

From: Multi-trait analysis for genome-wide association study of five psychiatric disorders

 

ADHD

ASD

DEP

BD

SCZ

GWAS

MTAG

GWAS

MTAG

GWAS

MTAG

GWAS

MTAG

GWAS

MTAG

SigSNPs

304

659

93

436

1890

3706

148

3343

8740

10609

Lead SNPs

15

21

3

10

49

63

8

63

87

110

Genomic locus

14

19

3

10

45

57

8

54

64

87

χ2

1.30

1.33

1.20

1.26

1.54

1.60

1.32

1.50

1.63

1.64

h2

0.23

0.33

0.19

0.35

0.04

0.05

0.35

0.70

0.42

0.51

Lambda GC

1.25

1.25

1.17

1.19

1.43

1.45

1.26

1.34

1.49

1.46

Intercept

1.03

0.95

1.01

0.92

1.01

0.98

1.02

0.89

1.05

0.95

Ratio

0.12

<0

0.04

<0

0.01

<0

0.05

<0

0.08

<0

Ngenes

20

13

43

121

254

24

17

160

136

269

Sample size

55,374

61,421

46,350

60,817

688,809

955,012

41,653

65,682

65,967

67,764

Overlapped SNPs

520,857

520,857

520,857

520,857

520,857

  1. SigSNPs number of significant SNPs; Ngenes number of genes.