Table 1 Statistical summary of GWAS and MTAG results.
From: Multi-trait analysis for genome-wide association study of five psychiatric disorders
ADHD | ASD | DEP | BD | SCZ | ||||||
---|---|---|---|---|---|---|---|---|---|---|
GWAS | MTAG | GWAS | MTAG | GWAS | MTAG | GWAS | MTAG | GWAS | MTAG | |
SigSNPs | 304 | 659 | 93 | 436 | 1890 | 3706 | 148 | 3343 | 8740 | 10609 |
Lead SNPs | 15 | 21 | 3 | 10 | 49 | 63 | 8 | 63 | 87 | 110 |
Genomic locus | 14 | 19 | 3 | 10 | 45 | 57 | 8 | 54 | 64 | 87 |
χ2 | 1.30 | 1.33 | 1.20 | 1.26 | 1.54 | 1.60 | 1.32 | 1.50 | 1.63 | 1.64 |
h2 | 0.23 | 0.33 | 0.19 | 0.35 | 0.04 | 0.05 | 0.35 | 0.70 | 0.42 | 0.51 |
Lambda GC | 1.25 | 1.25 | 1.17 | 1.19 | 1.43 | 1.45 | 1.26 | 1.34 | 1.49 | 1.46 |
Intercept | 1.03 | 0.95 | 1.01 | 0.92 | 1.01 | 0.98 | 1.02 | 0.89 | 1.05 | 0.95 |
Ratio | 0.12 | <0 | 0.04 | <0 | 0.01 | <0 | 0.05 | <0 | 0.08 | <0 |
Ngenes | 20 | 13 | 43 | 121 | 254 | 24 | 17 | 160 | 136 | 269 |
Sample size | 55,374 | 61,421 | 46,350 | 60,817 | 688,809 | 955,012 | 41,653 | 65,682 | 65,967 | 67,764 |
Overlapped SNPs | 520,857 | 520,857 | 520,857 | 520,857 | 520,857 |