Fig. 3: Mediation models. | Translational Psychiatry

Fig. 3: Mediation models.

From: Applying dimensional psychopathology: transdiagnostic associations among regional homogeneity, leptin and depressive symptoms

Fig. 3

a Path A represents the association between ReHo values in the primary somatosensory and visual association cortices and leptin. Path B represents the association between leptin and core depressive symptoms. Path C represents the association between ReHo values and core depressive symptoms. Path C represents the total effect of ReHo values on core depressive symptoms; and Path C’ shows the association between ReHo values and core depressive symptoms not through leptin; whereas path AB represents the indirect effect of ReHo values on core depressive symptoms mediated by leptin. b Path A represents the association between ReHo values in the primary somatosensory and visual association cortices and leptin. Path B represents the association between leptin and BMI. Path C represents the association between ReHo values and BMI. Path C represents the total effect of ReHo values on BMI; and Path C’ shows the association between ReHo values and BMI not through leptin; whereas path AB represents the indirect effect of ReHo values on BMI mediated by leptin. BMI body mass index, ReHo regional homogeneity.

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