Fig. 1: Polygenic transmission of ASD, comorbid disorders and BMI AS trios (N = 39), and Non_AS trios (N = 202). | Translational Psychiatry

Fig. 1: Polygenic transmission of ASD, comorbid disorders and BMI AS trios (N = 39), and Non_AS trios (N = 202).

From: Psychiatric comorbidities in Asperger syndrome are related with polygenic overlap and differ from other Autism subtypes

Fig. 1

Transmission disequilibrium is represented as standard deviations of the mid-parent distribution. Colored geometric lines represent 95% confidence intervals. P-values over geom error bars measure the probability that the mean of the pTDT deviation distribution is higher than 0 (two-sided, one-sample t-test). For each disorder, pTDT values were calculated based on the P threshold in which highest transmission were found for the whole ASD trios’ population (N = 379). Significant over-transmissions were confirmed with random permutation of AS subgroup. “*” Permutation P-value < 0.05; “+” Permutation P-value < 0.1.

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