Table 1 Polygenic transmission estimate values (from pTDT tests) of ASD and studied comorbid disorders (ASD, SCZ, MDD, ADHD, ANX, and OCD) in all ASD trios’ population (N = 379).

From: Psychiatric comorbidities in Asperger syndrome are related with polygenic overlap and differ from other Autism subtypes

P threshold

ASD

SCZ

MDD

ADHD

ANX

OCD

BMI

P < 0.001

−0.022

0.053

0.066

0.018

0.029

−0.083

0.064

P < 0.01

0.054

0.598

0.132

0.061

0.07

−0.047

0.027

P < 0.05

0.016

0.051

0.117

0.028

−0.013

−0.019

0.051

P < 0.1

0.02

0.03

0.058

0.049

0.005

−0.07

0.036

P < 0.2

0.034

0.063

0.022

0.033

−0.035

−0.047

0.039

P < 0.5

0.056

0.041

0.03

0.047

−0.049

−0.025

0.039

P < 1

0.054

0.041

0.055

0.035

−0.042

−0.023

0.04

  1. Several P thresholds (from GWAS summary statistics) were used in order to select the optimal cutoff for PRS calculation. highest transmission value from pTDT test in each case is marked in bold.
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