Table 2 Differentially methylated regions (DMRs) where MD affected twins exhibited higher means compared to MD unaffected twins and blood–brain correlationsa for CpGs within a DMR.
From: An epigenome-wide association study of early-onset major depression in monozygotic twins
Chr | Start | End | Symbol | EntrezID | Number CpGs | Empirical AUC | Median Bl–Br Corr | Min Bl–Br Corr | Max Bl–Br Corr |
|---|---|---|---|---|---|---|---|---|---|
chr1 | 36787678 | 36789401 | SH3D21 | 79729 | 3 | 3836.37 | −0.21 | −0.44 | −0.18 |
chr1 | 221053841 | 221055665 | HLX | 3142 | 4 | 4242.35 | 0.01 | −0.18 | 0.61 |
chr2 | 240035107 | 240036791 | HDAC4 | 9759 | 3 | 4057.64 | −0.08 | −0.16 | 0.15 |
chr5 | 1090741 | 1092417 | SLC12A7 | 10723 | 4 | 3818.33 | 0.08 | −0.09 | 0.43 |
chr5 | 171709917 | 171711524 | UBTD2 | 92181 | 3 | 4070.73 | 0.43 | 0.04 | 0.55 |
chr5 | 176936563 | 176938522 | DOK3 | 79930 | 6 | 3826.30 | −0.33 | −0.47 | 0.09 |
chr6 | 30519905 | 30521619 | NA | NA | 5 | 3861.90 | 0.41 | −0.19 | 0.55 |
chr6 | 31828260 | 31830030 | NA | NA | 4 | 4558.54 | 0.40 | 0.03 | 0.54 |
chr6 | 32797253 | 32798887 | NA | NA | 4 | 3849.67 | 0.24 | −0.18 | 0.44 |
chr6 | 39281541 | 39283313 | KCNK17 | 89822 | 3 | 4122.08 | −0.03 | −0.04 | 0.26 |
chr6 | 146863647 | 146865487 | RAB32 | 10981 | 7 | 4701.74 | −0.22 | −0.53 | 0.27 |
chr16 | 2023998 | 2025868 | TBL3 | 10607 | 4 | 4329.89 | 0.20 | −0.02 | 0.44 |
chr16 | 58767249 | 58769104 | GOT2 | 2806 | 4 | 4046.93 | 0.02 | −0.58 | 0.24 |
chr17 | 46659019 | 46660940 | HOXB3 | 3213 | 4 | 4501.78 | −0.05 | −0.24 | 0.03 |
chr17 | 70116185 | 70118162 | SOX9 | 6662 | 4 | 4120.22 | 0.27 | −0.10 | 0.50 |
chr19 | 13213428 | 13215387 | LYL1 | 4066 | 3 | 4381.78 | −0.33 | −0.44 | 0.04 |
chr21 | 38069321 | 38070994 | NA | NA | 4 | 3892.48 | −0.18 | −0.45 | 0.02 |
