Table 3 Variably methylated regions (VMRs) where MD affected twins exhibited greater variance compared to MD unaffected twins and blood–brain correlationsa for CpGs within a VMR.
From: An epigenome-wide association study of early-onset major depression in monozygotic twins
Chr | Start | End | Symbol | EntrezID | Number CpGs | Empirical AUC | Median Bl–Br Corr | Min Bl–Br Corr | Max Bl–Br Corr |
|---|---|---|---|---|---|---|---|---|---|
chr3 | 39321449 | 39323539 | CX3CR1b | 1524 | 4 | 5572.92 | 0.67 | −0.10 | 0.82 |
chr3 | 46925081 | 46925524 | PTH1R | 5745 | 2 | 5031.13 | 0.04 | −0.12 | 0.19 |
chr3 | 170136920 | 170137321 | CLDN11 | 5010 | 2 | 5110.24 | −0.12 | −0.45 | 0.22 |
chr6 | 32049516 | 32049825 | NA | NA | 3 | 5038.87 | 0.18 | 0.18 | 0.27 |
chr6 | 169284344 | 169287304 | NA | NA | 5 | 5276.01 | 0.27 | −0.04 | 0.31 |
chr6 | 170595385 | 170597898 | DLL1 | 28514 | 8 | 5628.62 | 0.38 | 0.16 | 0.61 |
chr7 | 157225062 | 157225567 | NA | NA | 2 | 5131.48 | 0.81 | 0.79 | 0.83 |
chr10 | 134739746 | 134741032 | CFAP46 | 54777 | 4 | 5667.46 | 0.13 | −0.30 | 0.16 |
chr11 | 64510112 | 64513156 | RASGRP2 | 10235 | 7 | 5458.44 | −0.12 | −0.37 | 0.84 |
chr17 | 40837037 | 40839469 | CNTNAP1 | 8506 | 4 | 5035.57 | 0.35 | 0.16 | 0.48 |
