Table 5 Coefficients and P-values of paths in structural equation models (SEMs) stratified by race, sex, and EBF1 rs4704963 genotypes, i.e., homozygote major allele (TT) and minor allele heterozygotes and homozygotes (CT/CC).
Race/sex | Genotype | Stress –> Waist | Waist –> GLUC | GLUC –> DM2 | Indirect path (stress –> Waist –> GLUC –> DM2) | ||||
|---|---|---|---|---|---|---|---|---|---|
Coef | P-value | Coef | P-value | Coef | P-value | Coef | P-value | ||
White female | CT/CC | 3.947 | <0.0001 | 0.026 | <0.0001 | 2.680 | <0.0001 | 0.280 | 0.009 |
TT | 1.571 | <0.0001 | 0.027 | <0.0001 | 2.188 | <0.0001 | 0.093 | 0.028 | |
White male | CT/CC | 0.680 | 0.012 | 0.022 | <0.0001 | 2.538 | 0.002 | 0.038 | 0.118 |
TT | 0.328 | 0.035 | 0.029 | <0.0001 | 2.455 | <0.0001 | 0.024 | 0.059 | |
Black female | CT/CC | 4.433 | <0.0001 | 0.019 | 0.013 | 2.016 | <0.0001 | 0.173 | 0.089 |
TT | 3.354 | <0.0001 | 0.030 | <0.0001 | 1.549 | <0.0001 | 0.158 | 0.035 | |
Black male | CT/CC | 1.766 | 0.082 | −0.003 | 0.878 | 1.745 | 0.003 | −0.008 | 0.888 |
TT | 0.149 | 0.734 | 0.026 | <0.0001 | 1.989 | <0.0001 | 0.008 | 0.716 | |