Table 5 Coefficients and P-values of paths in structural equation models (SEMs) stratified by race, sex, and EBF1 rs4704963 genotypes, i.e., homozygote major allele (TT) and minor allele heterozygotes and homozygotes (CT/CC).

From: Evaluating the precision of EBF1 SNP x stress interaction association: sex, race, and age differences in a big harmonized data set of 28,026 participants

Race/sex

Genotype

Stress –> Waist

Waist –> GLUC

GLUC –> DM2

Indirect path (stress –> Waist –> GLUC –> DM2)

Coef

P-value

Coef

P-value

Coef

P-value

Coef

P-value

White female

CT/CC

3.947

<0.0001

0.026

<0.0001

2.680

<0.0001

0.280

0.009

TT

1.571

<0.0001

0.027

<0.0001

2.188

<0.0001

0.093

0.028

White male

CT/CC

0.680

0.012

0.022

<0.0001

2.538

0.002

0.038

0.118

TT

0.328

0.035

0.029

<0.0001

2.455

<0.0001

0.024

0.059

Black female

CT/CC

4.433

<0.0001

0.019

0.013

2.016

<0.0001

0.173

0.089

TT

3.354

<0.0001

0.030

<0.0001

1.549

<0.0001

0.158

0.035

Black male

CT/CC

1.766

0.082

−0.003

0.878

1.745

0.003

−0.008

0.888

TT

0.149

0.734

0.026

<0.0001

1.989

<0.0001

0.008

0.716