Table 1 Associations of eight haplogroups in three European cohorts.
Study | Haplogroup | Ncase | Ncontrol | Fcase | Fcontrol | OR (95% CI) | P | Pcorrected |
---|---|---|---|---|---|---|---|---|
HH550 | OX | 8 | 34 | 1.05% | 1.67% | 0.62 (0.29,1.35) | 0.244 | 1 |
W | 17 | 31 | 2.23% | 1.53% | 1.47 (0.81,2.67) | 0.268 | 1 | |
K | 50 | 199 | 6.54% | 9.80% | 0.64 (0.47,0.89) | 4.43 × 10−3 | 0.035 | |
U | 94 | 292 | 12.30% | 14.38% | 0.84 (0.65,1.07) | 0.197 | 1 | |
J | 71 | 204 | 9.29% | 10.04% | 0.92 (0.69,1.22) | 0.653 | 1 | |
T | 74 | 184 | 9.69% | 9.06% | 1.08 (0.81,1.43) | 0.653 | 1 | |
I | 30 | 58 | 3.93% | 2.86% | 1.39 (0.89,2.18) | 0.13 | 1 | |
HHV* | 396 | 972 | 51.83% | 47.86% | 1.17 (0.99,1.38) | 0.071 | 0.564 | |
UK | 144 | 491 | 18.85% | 24.18% | 0.73 (0.59,0.9) | 2.63 × 10−3 | 0.021 | |
HH610 | OX | 7 | 32 | 1.08% | 1.60% | 0.67 (0.29,1.52) | 0.349 | 1 |
W | 10 | 32 | 1.54% | 1.60% | 0.96 (0.47,1.97) | 0.865 | 1 | |
K | 43 | 193 | 6.61% | 9.64% | 0.66 (0.47,0.93) | 0.011 | 0.084 | |
U | 73 | 304 | 11.21% | 15.18% | 0.71 (0.54,0.93) | 0.023 | 0.186 | |
J | 73 | 197 | 11.21% | 9.84% | 1.16 (0.87,1.54) | 0.269 | 1 | |
T | 70 | 196 | 10.75% | 9.79% | 1.11 (0.83,1.48) | 0.437 | 1 | |
I | 17 | 61 | 2.61% | 3.05% | 0.85 (0.5,1.47) | 0.684 | 1 | |
HHV* | 337 | 940 | 51.77% | 46.93% | 1.21 (1.02,1.45) | 0.086 | 0.69 | |
UK | 116 | 497 | 17.82% | 24.81% | 0.66 (0.52,0.82) | 3.08 × 10−4 | 2.46 × 10−3 | |
GSA | OX | 0 | 2 | 0.00% | 0.19% | 0 (0,Inf) | 0.972 | 1 |
W | 0 | 0 | 0.00% | 0.00% | NA | NA | NA | |
K | 46 | 98 | 6.96% | 9.39% | 0.72 (0.5,1.04) | 0.098 | 0.785 | |
U | 78 | 162 | 11.80% | 15.52% | 0.73 (0.55,0.97) | 0.046 | 0.368 | |
J | 55 | 88 | 8.32% | 8.43% | 0.99 (0.69,1.4) | 0.64 | 1 | |
T | 66 | 98 | 9.98% | 9.39% | 1.07 (0.77,1.49) | 0.574 | 1 | |
I | 19 | 32 | 2.87% | 3.07% | 0.94 (0.53,1.67) | 0.739 | 1 | |
HHV* | 350 | 500 | 52.95% | 47.89% | 1.22 (1.01,1.49) | 0.035 | 0.278 | |
UK | 124 | 260 | 18.76% | 24.90% | 0.7 (0.55,0.89) | 5.85 × 10−3 | 0.047 |