Table 1 Clinical outcomes.

From: Examining cognitive change in magnetic resonance-guided focused ultrasound capsulotomy for psychiatric illness

Subject

Diagnosis

Y-BOCS

HAM-D

  

Baseline

6 Months

12 Months

% Change

Baseline

6 Months

12 Months

% Change

1

OCD

39

21a

18a

−54

25

12

9

−64

2

OCD

30

27

19a

−37

8

10

7

−12.5

3

OCD

39

29

20a

−49

22

18

16

−27

4

OCD

29

23

23

−21

21

23

16

−24

5

OCD

40

39

36

−10

28

28

26

−7

6

MDD

 

25

19

3a

−88

7

MDD

 

23

19

25

+9

8

MDD

 

21

26

28

+33

9

MDD

 

25

26

25

0

10

MDD

 

21

27

30

+43

  1. OCD obsessive compulsive disorder, MDD major depressive disorder, Y-BOCS Yale-Brown Obsessive Compulsive Scale, HAM-D 17-item Hamilton Depression Rating Scale, % Change denotes change from baseline to 12 months, negative scores represent a decrease in symptoms postoperatively, whereas positive scores represent an increase in symptoms postoperatively.
  2. aIndicates that the subject met responder status as defined by ≥ 35% improvement on the Y-BOCS for patients with OCD and ≥ 50% improvement on the HAM-D for patients with MDD.