Table 1 Statistically significant result of MAGMA gene set analysis.
From: Synaptic processes and immune-related pathways implicated in Tourette syndrome
Gene set | Genes | P-value | Pcorr | ||||||
|---|---|---|---|---|---|---|---|---|---|
Cell adhesion and transsynaptic signaling | 72 | 6.1736e−05 | 0.00318 | ||||||
Gene ID | Chr | Start | End | SNPs | Param | N | Z-stat | P-value | Gene name |
60437 | 20 | 58528471 | 58593772 | 4 | 3 | 11263 | 4.2895 | 8.95e−06 | Cadherin 26 (CDH26) |
253559 | 3 | 85003133 | 86128579 | 42 | 18 | 11263 | 3.3124 | 0.00046 | Cell Adhesion molecule 2 (CADM2) |
4978 | 11 | 132279875 | 133407403 | 210 | 106 | 11263 | 3.1564 | 0.00079 | Opioid binding protein/cell adhesion molecule like (OPCML) |
1007 | 5 | 26875709 | 27043689 | 14 | 7 | 11263 | 2.9627 | 0.0015 | Cadherin 9 (CDH9) |
4685 | 21 | 22365633 | 22918892 | 61 | 29 | 11263 | 2.7975 | 0.0025 | Neural Cell adhesion molecule 2 (NCAM2) |
961 | 3 | 107756941 | 107814935 | 6 | 4 | 11263 | 2.6465 | 0.0040 | CD47 molecule (CD47) |
1003 | 16 | 66395525 | 66443689 | 11 | 6 | 11263 | 2.0242 | 0.021 | Cadherin 5 (CDH5) |
199731 | 19 | 44121519 | 44148991 | 4 | 3 | 11263 | 1.984 | 0.023 | CADM4 (cell adhesion molecule 4) |
708 | 17 | 5331099 | 5347471 | 1 | 1 | 11263 | 1.9269 | 0.026 | C1QBP (complement C1q binding protein) |
2017 | 11 | 70239612 | 70287690 | 2 | 2 | 11263 | 1.8709 | 0.030 | CTTN (cortactin) |
4045 | 3 | 115516210 | 116169385 | 56 | 29 | 11263 | 1.8095 | 0.035 | Limbic system-associated membrane protein (LSAMP) |
8502 | 2 | 159308476 | 159542941 | 19 | 9 | 11263 | 1.7503 | 0.040 | Plakophilin 4 (PKP4) |
5097 | 5 | 141227655 | 141263361 | 3 | 3 | 11263 | 1.6903 | 0.045 | PCDH1 (protocadherin 1) |
26047 | 7 | 145808453 | 148123090 | 237 | 110 | 11263 | 1.6621 | 0.048 | Contactin associated protein-like 2 (CNTNAP2) |
4155 | 18 | 74685789 | 74849774 | 49 | 30 | 11263 | 1.6502 | 0.049 | MBP (maltose-binding protein) |
