Table 3 Characteristics of the individuals with autoantibodies giving score 3 by IHC or positive for known or to novel NSAbs at wave 3.
From: Novel neuronal surface autoantibodies in plasma of patients with depression and anxiety
No. | Sex | Age (year) | IHC score/patterna | Titer by IHC | CBA | Staining on live neurons | Diagnosisb | Anxiety/depression onset age (year) | Anti-depressants usage during the last 2 years | Fever/coldc | Chronic comorbidities |
|---|---|---|---|---|---|---|---|---|---|---|---|
P1 | Male | 66 | 3/A | Not tested | Negative | Negative | Remitted depression | –/35 | No | No | Rheumatism: fibromyalgia; hay fever, house dust allergy |
P2 | Female | 46 | 3/B | 12800 | Negative | Positive | Current anxiety | 8/– | No | Cold | Hay fever |
P3 | Male | 55 | 3/B | 6400 | Negative | Positive | Current anxiety, remitted depression (single episode) | 53/14 | No | Cold | Hypertension |
P4 | Female | 58 | 3/B | 800 | Negative | Positive | Current anxiety and depression | 56/56 | No | Cold | Chronic bronchitis; diarrhea; eczema; psoriasis |
P5 | Female | 57 | 3/C | 3200 | Negative | Positive | Current anxiety | 55/– | No | Cold | Hypertension; breast cancer; eczema; arthritis; renal pelvic inflammation with encapsulated kidney stone; chronic heart conditions (unspecified) |
P6 | Female | 31 | 3/C | 3200 | Negative | Positive | Current anxiety, remitted depression (single episode) | 29/20 | No | No | No |
P7 | Female | 58 | 3/C | Not tested | Negative | Negative | Remitted anxiety and depression | 16/36 | No | No | Diabetes; arthritis; benign connective tissue tumor; allergy |
P8 | Male | 66 | 3/D | Not tested | Negative | Negative | Current depression | –/45 | Yes | No | No |
P9 | Male | 56 | 2/E | 1600 | Negative | Positive | Current anxiety, remitted depression (single episode) | 48/28 | No | No | Eczema |
P10 | Female | 36 | 2/F | 1600 | Negative | Positive | Current anxiety and depression | 35/34 | No | No | Chronic heart conditions (unspecified); ligament injury |
P11 | Male | 53 | 1/H | Not tested | CASPR2 positive (live and fixed CBA) | Negative | Remitted depression | –/51 | Yes | No | Hypertension; asthma; arthritis; hay fever; |
P12 | Male | 66 | 2/GAD pattern | Not tested | GAD65/67 positive | Negative | Current depression | –/61 | No | No | Diabetes, hypertension; arteriosclerosis, heart disease, chronic bronchitis; rheumatism; arthritis; constipation; |
C1 | Male | 20 | 2/K | 400 | Negative | Positive | None (Control group) | –/– | No | No | Injury (overloading of the knee) |
