Fig. 2: Phenol sulfotransferase activities in blood, post-mortem pineal glands, and ileal samples from patients with ASD.

a–c Blood samples were taken in the morning from 97 unrelated individuals with ASD, their first-degree relatives (138 parents and 56 unaffected sibs), and 106 controls. a Platelet PST-M activities. b Platelet PST-P activities. c, d Pineal gland samples were obtained from 9 patients with ASD and 22 age- and sex-matched controls. e, f Ileal samples were obtained from 13 patients with ASD and 11 matched controls. Boxes indicate medians and quartiles. Dashed lines indicate the threshold of the 5th percentiles of the control group. Groups were compared using the Wilcoxon two-sample test.