Fig. 4: The most differentially abundant taxa between the two groups.

a Heatmap of the 119 discriminative OTU abundances between WT and CD36−/− mice (LDA > 2.0). OTUs (raw) were sorted by taxa and enrichment. The intensity of the color (green to red) indicates the score normalized abundance for each OTU. b Associations of gut microbial family with behavioral phenotype. Heat map of Spearman’s rank correlation. Red squares indicate positive associations between microbial family and behavioral phenotype; blue squares indicate negative associations. The statistical significance level is indicated in the squares (n = 8–9 mice/group, *P < 0.05). SPT sucrose preference test, EIOA entrance in open arms, EICZ entrance in center zone.