Fig. 1: Study design and electrode placement. | Translational Psychiatry

Fig. 1: Study design and electrode placement.

From: Transcranial direct current stimulation induces long-term potentiation-like plasticity in the human visual cortex

Fig. 1

A Study design. Four different experimental conditions were used to modulate visually evoked potentials (VEPs), comprising a combination of either verum (+) or sham stimulation (−) for prolonged visual stimulation (PVS) and transcranial direct current stimulation (tDCS). Every participant performed the experiment over at least two sessions (PVS+/tDCS– and PVS+/tDCS+). Twenty-five participants underwent an additional test session (PVS−/tDCS+), and nine participants were randomized into the double sham control condition (PVS−/tDCS−). Baseline VEP recordings were conducted 2min prior to the stimulation block and experimental VEP recordings 4, 11, 22, 29, 40, and 47min after the stimulation block. B Electrode placement. Bioccipital anodal target electrodes were placed over the occipital cortex (O1 and O2, according to the 10–20 electrode positioning system; red), with cathodal return electrodes on the forehead (Fp1 and Fp2; blue). VEPs were recorded from the occipital region on the scalp (Oz; yellow) using a single active gold-cup electrode with a reference electrode placed on the forehead (Fpz; yellow).

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