Table 1 Overlap between treatment- and response-associated differentially expressed genes.

From: A distinct transcriptional signature of antidepressant response in hippocampal dentate gyrus granule cells

Gene name

Paroxetine vs vehicle

Good vs poor responder

Adenylate cyclase activating polypeptide 1

Adcyap1

AW551984

AW551984

Beta-site APP-cleaving enzyme 2

Bace2

Basonuclin 2

Bnc2

a

a

Cd24a

Cd24a

Muscarinic acetylcholine receptor M5

Chrm5

Dlk1

Dlk1

G protein-coupled receptor 101

Gpr101

5-hydroxytryptamine receptor 2C

Htr2c

Insulin-like growth factor binding protein 3

Igfbp3

Prolactin

Prl

a

a

Prolactin receptor

Prlr

a

a

Neuromedin-K receptor

Tacr3

Thyrotropin-releasing hormone receptor

Trhr

Vestigial like family member 3

Vgll3

  1. We detected 15 treatment- and response-associated genes that were differentially expressed in both experiments. For 12 of them, gene expression was altered in the same direction ↑ upregulated gene, ↓ downregulated gene.
  2. aThree of them (Bnc2, Prl, Prlr) showed the opposite regulation of gene expression.