Fig. 4: Enrichment of stable across age G × CA, stable in adults G × CA and non-consistent CpGs for GTEx upregulated gene sets.
From: Combined effects of genotype and childhood adversity shape variability of DNA methylation across age
The x-axis denotes the −log10(p value), and the y-axis the specific tissue type. Significant enrichments (based on FDR correction of 0.05) are depicted in blue, and nonsignificant in gray. For the group of nonconsistent CpGs, we randomly picked ten subsets of genes mapping to nonconsistent CpGs, equal in number to the genes mapping to stable across age G × CA CpGs. None of these subsets presented with significant adjusted p values for enrichment. In the plot, median p values across all subsets are depicted.
