Table 2 Comparison of Aβ-PET subgroups for plasma concentrations of the six identified brain-enriched miRNAs.

From: MiRNA-15b and miRNA-125b are associated with regional Aβ-PET and FDG-PET uptake in cognitively normal individuals with subjective memory complaints

 

Aβ-

Aβ+

p value

miRNA15b

0.83 (0.42–3.14)

0.49 (0.22–1.54)

0.045*

miRNA26b

0.66 (0.41–1.87)

0.46 (0.32–1.88)

n.s.

miRNA100

1.03 (0.62–1.48)

0.59 (0.41–1.43)

n.s.

miRNA125b

0.76 (0.55–1.09)

0.83 (0.58–1.07)

n.s.

miRNA146a

0.75 (0.42–1.62)

0.35 (0.29–1.33)

n.s.

miRNA148a

0.62 (0.43–1.34)

0.51 (0.30–1.27)

n.s.

  1. *Kruskal–Wallis one-way ANOVA on ranks test. Plasma miRNAs are reported in terms of median (IQ) of concentration (relative quantity).
  2. PET positron emission tomography, amyloid beta, n.s. not significant, miRNA microRNA.