Table 1 Body composition, tissue collection, and plasma measures.
Chow | Cycle | Cafeteria | Diet effect | |
---|---|---|---|---|
EchoMRI (3 days prior to kill) | ||||
Fat mass (g) | 46.8 ± 4.1 | 73.1 ± 6.8a | 126.1 ± 9.6a,b | p < 0.001 |
Fat percentage (%) | 14.2 ± 1.1 | 20.7 ± 1.4a | 29.5 ± 1.4a,b | p < 0.001 |
Lean mass (g) | 262.6 ± 6.5 | 256.2 ± 5.4 | 277.0 ± 7.4 | – |
Tissue collection | ||||
Final body weight (g) | 329.9 ± 7.9 | 367.0 ± 12.0 | 433.4 ± 17.3a,b | p < 0.001 |
Liver weight (g) | 9.95 ± 0.35 | 11.96 ± 0.54a | 12.68 ± 0.49a | p = 0.001 |
Retroperitoneal fat pad weight (g) | 4.81 ± 0.45 | 9.40 ± 1.14a | 13.15 ± 0.71a,b | p < 0.001 |
Ovary weight (mg) | 46.0 ± 2.1 | 44.7 ± 1.93 | 50.2 ± 2.4 | – |
Total oocytes/female | 20.5 ± 1.3 | 17.1 ± 1.5 | 15.1 ± 1.8a | p = 0.024 |
Blood/plasma measures | ||||
Blood glucose (mmol/L) | 7.7 ± 0.3 | 8.3 ± 0.3 | 9.3 ± 0.5a | p = 0.014 |
Plasma insulin (ng/mL) | 0.19 ± 0.05 | 0.91 ± 0.20a | 1.08 ± 0.22a | p = 0.002 |
Plasma leptin (ng/mL) | 5.69 ± 0.68 | 11.35 ± 1.28a | 17.38 ± 1.67a,b | p < 0.001 |
Plasma triglycerides (mmol/L) | 1.06 ± 0.08 | 2.30 ± 0.34a | 3.48 ± 0.49a | p = 0.001 |