Fig. 3: Distinct effects of OXTR variants on brain connectivity in males and females with autism. | Translational Psychiatry

Fig. 3: Distinct effects of OXTR variants on brain connectivity in males and females with autism.

From: Imaging-genetics of sex differences in ASD: distinct effects of OXTR variants on brain connectivity

Fig. 3

Top: Brain areas showing between-group differences as a function of sex and aggregate OXTR risk (z > 3.1, p < 0.05). Bottom, right: In ASD females, increased connectivity between the NAcc and left frontal pole is associated with lower social cognition T-scores on the SRS (indicative of less severe social-cognitive symptomatology).

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