Table 1 Suprathreshold clusters from activation likelihood estimation meta-analysis.

Brain region	MNI coordinates	SDM-Z	p	Voxels
Smoking cues minus neutral cues in smokers
Left anterior cingulate/paracingulate gyri, BA 32	−2, 50, 12	5.659	~0	8535
Left angular gyrus, BA 39	−52, −64, 24	3.213	0.00091	177
Right thalamus	4, −16, 4	3.364	0.00045	71
Corpus callosum	−2, 2, 6	3.058	0.00181	34
Right striatum	20, 10, 2	3.153	0.00119	27
Left middle temporal gyrus, BA 22	−54, −16, −2	−1.014	0.00024	621
Smokers minus Healthy controls in response to smoking cues
Right middle frontal gyrus, BA 46	38, 48, 4	1.506	0.00016	350
Right middle frontal gyrus, orbital part, BA 11	26, 38, −18	1.502	0.000186	264
Right lenticular nucleus, putamen	28, 4, 0	1.235	0.002276	71
Left superior frontal gyrus, dorsolateral, BA 6	−20, 6, 66	−1.037	0.001216	34
Smokers minus Healthy controls in response to nonsmoking reward cues
Right inferior parietal (excluding supramarginal and angular) gyri, BA 40	36, −54, 52	1.378	0.000006	826
Right insula, BA 47	34, 22, 0	1.377	0.000006	755
Right inferior frontal gyrus, opercular part, BA 44	52, 18,36	1.065	0.000275	296
Left striatum	−8, 12, −10	−2.662	~ 0	2987

Coordinates are given for the maximally significant voxel in each area, where x defines the lateral placement from the midline (left = negative), y defines the anteroposterior displacement relative to the anterior commissure (posterior = negative) and z defines the vertical position relative to the anteroposterior commissural line (down = negative). The coordinates are in Montreal Neurological Institute (MNI) space.

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