Fig. 3: Effect of minocycline on plasma CRP and serum metabolites. | Translational Psychiatry

Fig. 3: Effect of minocycline on plasma CRP and serum metabolites.

From: A single administration of the antibiotic, minocycline, reduces fear processing and improves implicit learning in healthy volunteers: analysis of the serum metabolome

Fig. 3

a Plasma CRP levels before and after placebo/minocycline administration expressed as a percentage change of before. Results are presented as mean + S.E.M. b Scores plot of the OPLS-DA model separating samples by treatment group. c Accuracy of the Minocycline/Placebo models were significantly better than that of the ensemble of randomly permuted models. d Representative images showing that differences in lipoprotein peaks were the key variables for building the OPLS-DA models. Spectra expressed as average of treatment group. Boxplot hinges depict 1st quartile to median (lower) and median to 3rd quartile (upper). *p < 0.05; ***p < 0.001.

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