Table 1 Group data for demographics, cannabis use data and genetics.

From: Do AKT1, COMT and FAAH influence reports of acute cannabis intoxication experiences in patients with first episode psychosis, controls and young adult cannabis users?

 

Whole sample (n = 720)

FEP patients (GAP) (n = 143)

GAP controls (n = 92)

YA cannabis users (485)

Test statistic

Age at testing (M(SD))

23.5 (6.6)

28.4 (8.36)

30.1 (9.5)

20.7 (1.8)

F(2,204.6) = 82.2, p ≤ 0.001, ɳ2 = 0.36a

Gender (N)

M: 489

F: 231

M: 97

F: 46

M: 52

F: 40

M: 340

F: 145

χ2(2) = 6.5, p = 0.038, V = 0.10

Ethnicity (N)

    

χ2(22) = 158.424, p ≤ 0.001, V = 0.30

 White British

359

49

44

266

 

 White Other

85

16

17

52

 

 Mixed

45

14

4

27

 

 Indian

38

0

2

36

 

 Pakistani

8

0

1

7

 

 Bangladeshi

5

4

0

1

 

 Other Asian

48

5

2

41

 

 Black Caribbean

50

26

15

9

 

 Black African

36

20

6

10

 

 Black other

3

3

0

0

 

 Chinese

17

1

0

16

 

 Other

25

5

1

19

 

Age of first cannabis use (M(SD))

15.3 (3.0)

16.3 (5.0)

16.3 (3.0)

14.9 (2.0)

F(2,166.53) = 10.04, p ≤ 0.001, ɳ2 = 0.04a

Years of cannabis use (M(SD))

6.34 (5.3)

10.06

9.95 (8.9)

4.8 (2.5)

F(2,155) = 31.8, p ≤ 0.001, ɳ2 = 0.19a

AKT1 (N)

635

102

70

436

χ2(4) = 2.27, p > 0.05, V = 0.04

 TT

160 (25.2%)

22 (21.6%)

17 (24.3%)

121 (26.1%)

 

 CT

326 (51.3%)

54 (52.9%)

40 (57.1%)

232 (50.1%)

 

 CC

149 (23.5%)

26 (25.5%)

13 (18.6%)

110 (23.8%)

 

HW stat

χ2 = 1.17, p > 0.05

χ2 = 0.37, p > 0.05

χ2 = 1.5, p > 0.05

χ2 = 0.0

p > 0.05

 

COMT (N)

657

113

91

453

χ2(4) = 16.93, p = 0.002, V = 0.11

 AA

143 (21.8%)

11 (9.7%)

15 (16.5%)

117 (25.8%)

 

 AG

316 (48.1%)

58 (51.3%)

46 (50.5%)

212 (46.8%)

 

 GG

198 (30.1%)

44 (38.9%)

30 (33%)

124 (27.4%)

 

HW stat

χ2 = 0.64 p > 0.05

χ2 = 0.9, p > 0.05

χ2 = 0.14, p > 0.05

χ2 = 1.8, p > 0.05

 

FAAH (N)

654

115

84

455

χ2(4) = 12.24, p = 0.016, V = 0.10

 CC

409 (62.5%)

71 (61.7%)

42 (50%)

296 (65.1%)

 

 AC

206 (31.5%)

39 (33.9%)

21 (36.9%)

136 (29.9%)

 

 AA

39 (6.0%)

5 (4.3%)

11 (13.1%)

23 (5.1%)

 

 Cannabis-induced –Psychotic-Like experiences (M(SD))

9.26 (3.68)

10.54 (4.74)

8.90 (3.16)

9.00 (3.33)

F(2,288.58) = 9.43, p ≤ 0.001, ɳ2 = 0.02a

 Cannabis- induced Euphoric Experiences (M(SD))

17.86 (5.97)

16.91 (7.20)

15.28 (5.96)

M = 18.6 (5.38)

F(2, 293.85) = 12.57 p < 0.001, ɳ2 = 0.04a

  1. HW Hardy Weinberg, ɳ2 eta squared, V Cramer’s V.
  2. aBrown-Forsyth Test.
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