Fig. 1: Genes shared between PNDs.
From: Drug repositioning for psychiatric and neurological disorders through a network medicine approach
a A knowledge network for genes colored according to Louvain-defined modules: Alzheimer’s disease (AD) and dementia (DM) (purple), Huntington’s disease (HD) and Parkinson’s disease (PKD; light blue), depression (MDD) and anxiety (AX; red), schizophrenia (SCZ) and bipolar disorder (BD; green-yellow), and autism (ASD; green). The dashed line in a separates neurodegenerative disorders from psychiatric disorders in the network. b The significance of the gene overlap between PNDs. Larger nodes represent PNDs with more genes and thicker edges represent a more significant overlap between PNDs (proportional to −log10p-value of Fisher’s exact test).
