Table 3 The correlations between cerebrospinal fluid neuroplasticity-associated protein levels and symptom scores.

From: Cerebrospinal fluid neuroplasticity-associated protein levels in patients with psychiatric disorders: a multiplex immunoassay study

	Schizophrenia								Bipolar disorder				Major depressive disorder
	PANSS total		PANSS positive		PANSS negative		PANSS general		Young Mania Rating Scale		HAMD-21		HAMD-21		Core		Sleep		Activity		Psychic anxiety		Somatic anxiety		Delusion
	r	p	r	p	r	p	r	p	r	p	r	p	r	p	r	p	r	p	r	p	r	p	r	p	r	p
APP	0.06	0.55	0.12	0.27	−0.02	0.88	0.06	0.60	−0.03	0.85	−0.14	0.28	0.07	0.51	0.06	0.59	0.06	0.57	0.03	0.75	0.01	0.96	0.06	0.59	0.04	0.71
Contactin-1	−0.01	0.90	0.06	0.59	−0.08	0.47	−0.01	0.92	−0.01	0.92	−0.08	0.53	0.08	0.46	0.06	0.59	0.08	0.43	0.00	0.98	0.00	0.96	0.08	0.43	0.08	0.43
ErbB3	0.09	0.42	0.20	0.06	−0.07	0.50	0.09	0.42	−0.01	0.96	−0.08	0.56	0.17	0.09	0.16	0.11	0.14	0.17	0.07	0.50	0.11	0.27	0.10	0.33	0.19	0.07
GDNF	0.03	0.76	0.19	0.07	−0.11	0.30	0.01	0.89	0.13	0.33	−0.07	0.59	0.15	0.15	0.18	0.08	−0.03	0.79	0.13	0.21	0.16	0.13	0.11	0.28	0.16	0.11
HGF	0.34	0.001	0.34	0.001	0.16	0.13	0.31	0.003	0.00	1.00	0.02	0.86	0.27	0.008	0.23	0.023	0.21	0.041	0.22	0.034	0.12	0.24	0.25	0.015	0.22	0.030
HGF receptor	0.01	0.89	0.03	0.80	−0.02	0.86	0.02	0.84	−0.06	0.68	−0.01	0.93	0.10	0.31	0.07	0.53	0.11	0.31	0.00	0.99	0.02	0.83	0.15	0.15	0.09	0.40
NCAM-1	−0.04	0.72	0.03	0.79	−0.08	0.43	−0.04	0.74	0.00	0.98	−0.12	0.34	0.06	0.55	0.04	0.69	0.06	0.54	0.00	0.97	0.02	0.85	0.08	0.41	0.05	0.66
Neuropilin-1	−0.01	0.94	0.01	0.95	0.01	0.94	−0.02	0.82	0.03	0.82	−0.11	0.38	0.13	0.20	0.12	0.24	0.11	0.29	0.08	0.44	0.11	0.30	0.10	0.32	0.08	0.44
S100B	0.28	0.007	0.21	0.044	0.15	0.15	0.30	0.005	0.28	0.041	0.00	0.98	0.19	0.06	0.16	0.11	0.22	0.031	0.13	0.21	0.03	0.74	0.10	0.33	0.17	0.10
VEGF receptor 1	−0.11	0.31	−0.09	0.40	−0.06	0.58	−0.11	0.31	−0.02	0.89	−0.02	0.88	0.06	0.55	0.04	0.73	0.16	0.12	0.00	0.98	0.08	0.42	−0.02	0.87	0.02	0.84
VEGF receptor 2	0.04	0.73	0.01	0.90	0.06	0.59	0.02	0.84	0.10	0.45	−0.11	0.41	0.20	0.05	0.14	0.16	0.22	0.028	0.09	0.39	0.16	0.13	0.17	0.10	0.17	0.09

APP amyloid precursor protein, GDNF glial cell line-derived neurotrophic factor, HAMD-21 21-item version Hamilton Depression Rating Scale, HGF hepatocyte growth factor, NCAM neural cell adhesion molecule, PANSS positive and negative syndrome scale, S100B S100 calcium-binding protein B, VEGF vascular endothelial growth factor.
r, Pearson’s partial correlation cofficient (covariates: age, sex and drug use).
Significant p values are shown in bold cases (correctely significant cases are underlined, p < 0.0045).

Back to article page

Table 3 The correlations between cerebrospinal fluid neuroplasticity-associated protein levels and symptom scores.

Search

Quick links