Table 3 Measurements of phenolic acids in plasma following FRP treatment.

From: Prophylactic effect of flavanol rich preparation metabolites in promoting resilience to a mouse model of social stress

Phenolic acids

Vehicle CTRL

40 mg/kg/day

200 mg/kg/day

 

Average (nM)

St dev

Average (nM)

St dev

Average (nM)

St dev

GAa

38.9

12.4

72.3

23.5

126.4

31.8

3,4-diHBAa

14.0

11.7

185.9

47.3

247.8

73.4

3,4-diHPPA

459.2

59.2

566.6

139.0

525.8

133.8

4-HBA

4174.6

191.6

4335.2

253.7

4152.1

184.9

HAa

10.5

14.4

125.7

65.0

641.7

566.6

VAb

555.2

63.1

667.4

99.8

614.9

40.8

3-HBA

579.4

10.3

578.7

12.4

587.8

12.0

3-HPPAb

1046.8

32.8

1228.7

125.1

1039.8

51.4

HVAb

5161.8

470.9

8952.9

1950.4

7045.7

1048.6

diHCA

205123.3

5945.6

195755.1

6280.6

174706.9

15465.6

4-HCAb

1535.3

224.6

3456.7

1119.1

2670.5

738.4

3-HPPA

468.5

4.6

505.0

60.8

513.1

18.8

FA

308.8

9.5

360.1

40.3

352.8

21.9

4-HPVA

0.0

0.0

Trace

0.0

31.4

11.4

  1. Plasma levels phenolic acids measured 6 h following the last dosing in mice treated with vehicle, 40 mg/kg/day or 200 mg/kg/day of FRP for 2 weeks.
  2. aPhenolic content significantly higher in the 200 mg/kg/day group compared to 40 mg/kg/day group.
  3. bPhenolic content significantly higher in the 40 mg/kg/day group compared to 200 mg/kg/day group, n = 5 for vehicle control, n = 7–8 for treatment group.
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