Fig. 2: Sorcs2−/− mice have lower sucrose intake.

A Identical water intake in Wt and Sorcs2−/− mice during a period of 48 h when water was the only drinking source (Student’s unpaired t-test, p > 0.9). B, C Cumulative intake of 4% sucrose solution of Wt and Sorcs2−/− mice in a two-bottle test paradigm. Reduced consumption of sucrose-containing solution in Sorcs2−/− mice compared to Wt mice displayed as AUC (p < 0.0001, Student’s unpaired t-test). D Sucrose preference (Student’s un-paired t-test p > 0.5). E Water intake during the three days of experiment (p > 0.15, Student’s unpaired t-test). F The weights of Wt and Sorcs2−/− mice were not significantly different (p > 0.16, Student’s unpaired t-test). 4 mice of each genotype were tested. **** p < 0.0001.