Fig. 3: Juvenile offspring neurobiology was altered by maternal AVP.
From: Altered offspring neurodevelopment in an arginine vasopressin preeclampsia model
a Cortical volume in postnatal day 7 (P7) offspring was trend-smaller in males (p = 0.054) and significantly smaller in AVP-exposed females (p = 0.047). b Cortical cell density and (c) cell number were not changed by AVP at P7, (d) nor was corpus callosum volume, in either sex. e The caudate–putamen was smaller by volume in P7 male AVP-exposed offspring (p = 0.032), while (f) caudate–putamen volume relative to cortical volume was increased among P7 AVP-exposed females (p = 0.043). g The density of cells in the caudate was increased in P7 AVP-exposed males (p = 0.046), resulting in (h) an unchanged number of cells with AVP exposure in either sex. *p < 0.05 per two-sample t-test, error bars represent SEM. 2 litters per condition, 2–3 brains per sex per litter.
