Table 3 Patient Rated Inventory of Side Effects (PRISE) counts of symptoms (rated tolerable or distressing) 60 mins post oral ketamine administration by treatment week (n = 32).
From: Low dose oral ketamine treatment in chronic suicidality: An open-label pilot study
Treatment week | 1 | 2 | 3 | 4 | 5 | 6 |
|---|---|---|---|---|---|---|
Ntolerable/Ndistressing | ||||||
Decreased energy | 17/14 | 23/7 | 21/7 | 21/8 | 18/7 | 23/3 |
Fatigue | 18/12 | 20/11 | 18/10 | 20/8 | 18/7 | 19/7 |
Anxiety | 11/18 | 21/7 | 20/9 | 23/3 | 15/9 | 21/3 |
Poor concentration | 16/13 | 22/6 | 19/7 | 18/7 | 20/4 | 19/2 |
Restlessness | 19/5 | 15/3 | 17/4 | 14/3 | 15/3 | 16/1 |
General malaise discomfort | 14/7 | 18/3 | 14/2 | 10/3 | 13/2 | 12/2 |
Dry mouth | 17/1 | 15/3 | 18/2 | 19/2 | 15/2 | 18/1 |
Headache | 16/1 | 19/2 | 15/3 | 14/1 | 15/1 | 12/3 |
Dizziness on standing | 15/1 | 12/0 | 11/0 | 13/0 | 11/1 | 11/0 |
Tremors | 13/2 | 10/1 | 9/2 | 11/1 | 9/1 | 9/0 |
Dry skin | 13/0 | 12/0 | 12/0 | 14/0 | 13/0 | 13/0 |
Dizziness | 13/0 | 10/0 | 13/0 | 9/0 | 9/0 | 11/0 |
Ringing in ears | 10/2 | 8/0 | 7/1 | 5/1 | 5/1 | 7/1 |
Palpitation | 10/1 | 12/0 | 9/1 | 8/0 | 8/0 | 6/0 |
Itching | 10/0 | 8/0 | 8/0 | 8/0 | 7/0 | 5/1 |
Frequent urination | 9/0 | 7/1 | 8/0 | 10/0 | 7/1 | 11/1 |
Blurred vision | 8/0 | 3/0 | 5/0 | 6/0 | 6/0 | 7/0 |
Increased perspiration | 8/0 | 4/0 | 4/0 | 4/0 | 3/0 | 3/1 |
Poor coordination | 7/1 | 3/1 | 7/0 | 7/1 | 10/1 | 7/1 |
Rash | 7/0 | 4/0 | 5/0 | 5/0 | 5/0 | 4/0 |
Nausea vomiting | 6/0 | 7/1 | 7/1 | 10/0 | 6/1 | 11/0 |
Chest pain | 4/1 | 3/0 | 1/0 | 2/0 | 2/0 | 5/0 |
Diarrhoea | 4/0 | 6/1 | 6/0 | 4/0 | 5/0 | 5/0 |
Other | 3/1 | 3/2 | 0/0 | 2/1 | 3/0 | 1/1 |
Constipation | 3/0 | 7/0 | 5/0 | 7/0 | 9/0 | 9/0 |
Difficulty urinating | 2/0 | 2/0 | 2/0 | 2/0 | 2/0 | 1/0 |
Painful urination | 1/0 | 1/0 | 1/0 | 1/0 | 2/0 | 2/0 |
