Table 1 Demographic and clinical characteristics and distribution of atypical symptoms in CoLaus|PsyCoLaus and NESDA|NTR.

From: Obesity and atypical depression symptoms: findings from Mendelian randomization in two European cohorts

 

CoLaus|PsyCoLaus

NESDA | NTR

MDD

Atypical MDD

No MDD

Participants endorsing atypical symptoms

MDD

Atypical MDD

No MDD

Participants endorsing atypical symptoms

Total N

1461

386

1889

1958

1182

179

2957

4139

Female (%)

66.12

72.54

43.41

63.02

68.52

70.39

60.97

63.13

Mean year of birth (SD)

1955 (8.5)

1955 (8.3)

1954 (8.7)

1955 (8.5)

1962 (12.5)

1963 (12.1)

1963 (15.7)

1963 (14.9)

Number of episodes (%):

1 episode

59.07

48.70

1.70

1.60

2 episodes

22.38

25.91

22.60

16.10

>2 episodes

18.48

25.39

75.70

82.30

Mean age of onset (SD)

33.81 (12.9)

33.10 (13.4)

27.8 (12.9)

24.3 (12.4)

Increase in appetite (%)

17.18

40.67

14.15

8.79

37.43

2.51

Hypersomnia (%)

24.84

48.70

20.38

15.31

56.98

4.37

Mood reactivity (%)

69.95

100.00

72.37

32.82

100.00

9.37

Leaden paralysis (%)

29.77

59.06

24.41

23.60

81.56

6.74

Rejection sensitivity (%)

66.11

90.15

61.08

19.96

75.42

5.70

  1. Number of episodes available in 59% of NESDA|NTR MDD cases and 69% of NESDA|NTR atypical MDD cases.