Table 2 Enrichment for dysregulated expression of putative psychiatric illness risk gene orthologues in Der1 cortex and hippocampus.

GWAS, schizophrenia¹

108

348

121 genes at 61 loci

p = 1e−13 (p = 8e−19)

6 genes at 6 loci

p = 0.04 (p = 2e−4)

GWAS, schizophrenia²

143

481

127 genes at 73 loci

p = 3e−6 (p = 8e−19)

6 genes at 6 loci

p = 0.09 (p = 8e−4)

MAGMA, schizophrenia²

535

210

p = 3e−30

15

p = 2e−5

CNV (synapse genes), schizophrenia³

52

25

p = 8e−7

4

p = 7e−4

GWAS, depression⁴

44

70

19 at 19 loci

p = 0.02 (p = 9e−5)

1

ns

MAGMA, depression⁴

153

33

p = 0.047

1

ns

MAGMA meta-analysis, depression⁶

269

94

p = 4e−11

6

p = 0.01

GWAS, bipolar disorder⁵

30

218

73 at 21 loci

p = 4e−8 (p = 8e−10)

3 genes at 3 loci

ns (p = 2e−3)

MAGMA, bipolar disorder⁵

152

49

p = 2e−5

3

p = 0.09

GWAS, Alzheimer’s Disease⁵⁵

21

102

9 at 9 loci

p = 3e−3 (p = 6e−3)

1

ns

GWAS cerebral cortex architecture⁶⁵

193

57

p = 5e−5

1

ns