Fig. 1: Activation of Nrf2 inhibits BDNF transcriptional repressor (MeCP2, HDAC2, and mSin3a) expression in Neuro-2a cell.

A, B The quantitative real-time PCR for Nrf2 and Bdnf (mean ± SEM, n = 3 per group, one-way ANOVA, **p < 0.01 and ***p < 0.01). C The representative image for western blot. D The quantitative result for Nrf2. E The quantitative result for BDNF. F The quantitative result for HDAC2. G The quantitative result for mSin3A. H The quantitative result for MeCP2 (mean ± SEM, n = 3 per group, one-way ANOVA, *p < 0.05, **p < 0.01, and ***p < 0.01).