Table 1 Demographic characteristics at baseline and follow-ups (FU) 1, 2, and 3.

From: Volumetric trajectories of hippocampal subfields and amygdala nuclei influenced by adolescent alcohol use and lifetime trauma

 

Overalla

n = 2684

Baselinea

n = 803

FU1a

n = 739

FU2a

n = 651

FU3a

n = 491

p-valueb

Age at scan (years)

17.58 (2.73)

[12.02–25.07]

16.21 (2.52)

[12.02–21.96]

17.30 (2.49)

[12.99–22.93]

18.29 (2.46)

[13.98–23.98]

19.32 (2.49)

[14.92–25.07]

<0.001

Sex

     

>0.9

 F

1380 (51%)

412 (51%)

381 (52%)

332 (51%)

255 (52%)

 

 M

1304 (49%)

391 (49%)

358 (48%)

319 (49%)

236 (48%)

 

Race

 African-American/Black

310 (12%)

96 (12%)

87 (12%)

73 (11%)

54 (11%)

 

 African-American and Caucasian

29 (1.1%)

9 (1.1%)

8 (1.1%)

8 (1.2%)

4 (0.8%)

 

 Asian

210 (7.8%)

64 (8.0%)

59 (8.0%)

51 (7.8%)

36 (7.3%)

 

 Asian Pacific Islander

4 (0.1%)

1 (0.1%)

1 (0.1%)

1 (0.2%)

1 (0.2%)

 

 Asian and White

74 (2.8%)

21 (2.6%)

20 (2.7%)

19 (2.9%)

14 (2.9%)

 

 Caucasian/White

2024 (75%)

600 (75%)

555 (75%)

491 (75%)

378 (77%)

 

 Native American/American Indian

7 (0.3%)

3 (0.4%)

2 (0.3%)

2 (0.3%)

0 (0%)

 

 Native American and Caucasian

5 (0.2%)

2 (0.2%)

1 (0.1%)

1 (0.2%)

1 (0.2%)

 

 None

6 (0.2%)

2 (0.2%)

2 (0.3%)

1 (0.2%)

1 (0.2%)

 

 Pacific Islander

12 (0.4%)

4 (0.5%)

3 (0.4%)

3 (0.5%)

2 (0.4%)

 

 Pacific Islander and Caucasian

3 (0.1%)

1 (0.1%)

1 (0.1%)

1 (0.2%)

0 (0%)

 

 SES

16.79 (2.47)

[6.00–20.00]

16.79 (2.49)

[6.00–20.00]

16.83 (2.45)

[6.00–20.00]

16.81 (2.48)

[6.00–20.00]

16.71 (2.45)

[6.00–20.00]

0.8

Family AUD density

 0

2008 (75%)

601 (75%)

554 (75%)

487 (75%)

366 (75%)

 

 0.5

392 (15%)

117 (15%)

108 (15%)

96 (15%)

71 (14%)

 

 1

158 (5.9%)

46 (5.7%)

42 (5.7%)

39 (6.0%)

31 (6.3%)

 

 1.5

72 (2.7%)

22 (2.7%)

19 (2.6%)

17 (2.6%)

14 (2.9%)

 

 2

45 (1.7%)

14 (1.7%)

13 (1.8%)

10 (1.5%)

8 (1.6%)

 

 2.5

4 (0.1%)

1 (0.1%)

1 (0.1%)

1 (0.2%)

1 (0.2%)

 

 3

3 (0.1%)

1 (0.1%)

1 (0.1%)

1 (0.2%)

0 (0%)

 

 4

2 (<0.1%)

1 (0.1%)

1 (0.1%)

0 (0%)

0 (0%)

 

Drinking class (Cahalan scale)

     

<0.001

 0

1800 (67%)

642 (80%)

512 (69%)

385 (59%)

261 (53%)

 

 1

471 (18%)

110 (14%)

122 (17%)

131 (20%)

108 (22%)

 

 2

106 (3.9%)

12 (1.5%)

19 (2.6%)

32 (4.9%)

43 (8.8%)

 
 

307 (11%)

39 (4.9%)

86 (12%)

103 (16%)

79 (16%)

 

Baseline trauma (# of events)

     

>0.9

 0

1029 (38%)

305 (38%)

286 (39%)

251 (39%)

187 (38%)

 

 1

887 (33%)

265 (33%)

239 (32%)

218 (33%)

165 (34%)

 

 2

508 (19%)

154 (19%)

144 (19%)

121 (19%)

89 (18%)

 

 3

181 (6.7%)

56 (7.0%)

49 (6.6%)

42 (6.5%)

34 (6.9%)

 

 4

79 (2.9%)

23 (2.9%)

21 (2.8%)

19 (2.9%)

16 (3.3%)

 

Lifetime marijuana use (days)

26.15 (137.2)

[0–2309]

8.80 (86.3)

[0–1712]

16.78 (103.9)

[0–1738]

32.80 (146.5)

[0–2119]

59.82 (210.7)

[0–2309]

<0.001

Lifetime tobacco use (days)

19.37 (247.6)

[0–10796]

3.11 (36.4)

[0–900]

12.39 (106.4)

[0–1827]

19.80 (169.9)

[0–3656]

55.92 (525.6)

[0–10,796]

<0.001

  1. n (%).
  2. aStatistics presented: mean (SD) [minimum-maximum].
  3. bStatistical tests performed: Kruskal–Wallis test; chi-square test of independence.
  4. Bold values indicates statistical significant p-values (p < 0.05).