Fig. 2: Characterizing synaptosome engulfment by CB-iMGs in an in vitro model of synaptic pruning. | Translational Psychiatry

Fig. 2: Characterizing synaptosome engulfment by CB-iMGs in an in vitro model of synaptic pruning.

From: Umbilical cord blood-derived microglia-like cells to model COVID-19 exposure

Fig. 2

a Overall schematic of pHrodo-labeled quantitative synaptosome phagocytosis assay by CB-iMGs. b Representative live real-time images in phase contrast/red fluorescence overlay mode showing cellular uptake and c red fluorescence channel alone of pHrodo (red)-labeled synaptosomes uptake at the end of the phagocytosis assay (315 min). Scale bar: 60 μm (boxes show magnified view of engulfing CB-iMG).

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