Fig. 3: Participant Outcomes. | Translational Psychiatry

Fig. 3: Participant Outcomes.

From: A randomised, double-blind, sham-controlled trial of deep brain stimulation of the bed nucleus of the stria terminalis for treatment-resistant obsessive-compulsive disorder

Fig. 3

A, B Time series of individual participant outcomes for primary (YBOCS) and secondary (MADRS) variables. Within each graph, group-average trajectory is represented by a loess smoothed curve (white) ± 1 standard error (grey). Baseline measurement denoted by green outline, recovery phase by yellow outline and blinded phase by red outline. C, D Boxplots of YBOCS and MADRS change by randomised group (on = green versus off = red) during the blinded phase. E, F Raincloud plots of YBOCS and MADRS change across the full trial. Raincloud plots made with code provided by Allen et al.75. and van Langen76. G, H Trajectories of the participants by group (active versus sham) in the blinded phase. There were five participants in the active group and four in the sham group.

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