Fig. 2: Comparisons of the behavioral test results of mice in different groups. | Translational Psychiatry

Fig. 2: Comparisons of the behavioral test results of mice in different groups.

From: Hippocampal PGC-1α-mediated positive effects on parvalbumin interneurons are required for the antidepressant effects of running exercise

Fig. 2

A Schematic showing the positions of adeno-associated virus injection in hippocampus of mice. B Schematic showing behavior experiment timeline. The behavioral tests include SPT, FST and TST. C–E The sucrose preference and immobility time in the FST and TST (mean ± SD) of mice in AAV-GFP group (n = 30) and the AAV-PGC-1α group (n = 31) before running exercise. * indicates p < 0.05, and ** indicates p < 0.001. F–H The sucrose preference and immobility time in the FST and TST (mean ± SD) of mice in the AAV-GFP group (n = 15) and AAV-PGC-1α group (n = 15), AAV-GFP + RN group (n = 15) and AAV-PGC-1α + RN group (n = 16) after running exercise. * indicates p < 0.05.

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