Fig. 4: Comparisons of the cFos+/PV+ cells in the DG, CA1, and CA3 subfields of the hippocampus of the mice in different groups. | Translational Psychiatry

Fig. 4: Comparisons of the cFos+/PV+ cells in the DG, CA1, and CA3 subfields of the hippocampus of the mice in different groups.

From: Hippocampal PGC-1α-mediated positive effects on parvalbumin interneurons are required for the antidepressant effects of running exercise

Fig. 4

A Representative pictures of immunofluorescence staining with anti-PV antibody and anti-cFos antibody in the hippocampus in the four groups. The white arrows show the cFos+/PV+ cells. PV: green, c-Fos: red. Scale bar = 100 μm. B Quantification of the cFos/PV cell number in the hippocampus in the AAV-GFP group (n = 4), AAV-PGC-1α group (n = 5), AAV-GFP + RN group (n = 4) and AAV-PGC-1α + RN group (n = 5) of mice after immunofluorescence staining (mean ± SD). * indicates p < 0.05, and ** indicates p < 0.001.

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