Table 1 Basic information of the eQTL and GWAS data.

From: Mendelian randomization integrating GWAS and eQTL data revealed genes pleiotropically associated with major depressive disorder

Data source

Total participants or cases/controls

Number of genetic variants or probes

eQTL data

 Amygdala

129

779

 Anterior cingulate cortex

147

1379

 Caudate

194

2089

 Cerebellar hemisphere

175

2615

 Cerebellum

209

3765

 Cortex

205

2314

 Frontal cortex

175

1722

 Hippocampus

165

1108

 Hypothalamus

170

1170

 Nucleus accumbens

202

1785

 Putamen

170

1449

 Spinal cord

126

915

 Substantia nigra

114

661

 Brain-eMeta

1194

7421

GWAS-Meta

246,363/561,190

8,098,588

 23andme_307k

75,607/231,747

 

 UK Biobank

127,552/233,763

 

 PGC_139k

43,204/95,680

 
  1. GWAS genome-wide association studies, QTL quantitative trait loci, PGC Psychiatric Genomics Consortium.