Table 1 Genome-wide significant loci identified in this study.
From: Genome wide association study identifies four loci for early onset schizophrenia
Chra | Position | Index SNP | A1/A2 | Discovery stage (1256 cases/2661 controls) | Replication stage (903 cases/3900 controls) | Meta-analysis (2159 cases/6561 controls) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
P | ORb | AFc | P | OR | AF | Pd | OR | Ie | ||||
1 | 11856378 | rs1801133 | A/G | 7.48 × 10−05 | 1.24 | 0.59/0.50 | 1.20 × 10−12 | 1.45 | 0.54/0.45 | 4.03 × 10−15 | 1.35 | 82.65 |
1 | 82919925 | rs1281571 | A/G | 6.44 × 10−05 | 1.24 | 0.44/0.40 | 1.70 × 10−04 | 1.22 | 0.45/0.40 | 4.14 × 10−08 | 1.23 | 0 |
3 | 46485369 | rs7626288 | A/G | 9.08 × 10−05 | 0.81 | 0.39/0.43 | 3.63 × 10−06 | 0.78 | 0.38/0.44 | 1.57 × 10−09 | 0.80 | 0 |
9 | 129673226 | rs592927 | A/G | 4.21 × 10−05 | 1.30 | 0.24/0.20 | 1.56 × 10−07 | 1.38 | 0.25/0.19 | 4.01 × 10−11 | 1.34 | 0 |
