Table 1 Characteristics of Alzheimer’s disease and control participants.

From: Plasma lipidome is dysregulated in Alzheimer’s disease and is associated with disease risk genes

 

Healthy controls (n = 42)

Alzheimer’s disease (n = 40)

Difference

Age(years)

81.27(2.48)

86.72(5.03)

t = 6.270, p < 0.01

Sex (males/females)

19/23

23/17

χ2 = 1.233, p = 0.267

Oligomeric Aβ (OD value)

0.25(0.05)

0.40(0.10)

t = 6.391, p < 0.01

Education (years)

11.30(3.59)

11.59(3.64)

t = 0.363, p = 0.717

Body mass index

26.69(3.19)

25.45(3.72)

t = 1.631, p = 0.107

Diabetes

7.10%

15%

χ2 = 1.294, p = 0.255

Hypertension

61.90%

77.50%

χ2 = 2.351, p = 0.125

Anti-hypertensive medication

60.00%

54.30%

χ2 = 0.249, p = 0.618

Anti-hyperlipidemia medication

64.30%

50.00%

χ2 = 1.709, p = 0.791

Current smoker

9.50%

5.00%

χ2 = 0.618, p = 0.432

APOE*4 carriers

19%

37.50%

χ2 = 3.457, p = 0.063

MMSE

28.21(1.58)

22.63(3.86)

t = 8.557, p < 0.01

  1. Continuous variables are expressed as means and standard deviations. Categorical variables are expressed as %.
  2. APOE*4 apolipoprotein epsilon 4, MMSE Mini-mental state examination.