Table 2 GLMnet results of lipid models in the classification of AD versus control.

From: Plasma lipidome is dysregulated in Alzheimer’s disease and is associated with disease risk genes

Lipid models

Sensitivity

Specificity

AUC

All_lipids

0.66

0.73

0.78

Cer

0.7

0.79

0.79

ChE

0.78

0.75

0.82

DG

0.72

0.69

0.76

LPC

0.49

0.62

0.58

PC

0.69

0.76

0.78

PE

0.58

0.5

0.57

PI

0.7

0.76

0.79

SM

0.71

0.78

0.83

TG

0.65

0.82

0.83

SM_TG

0.69

0.75

0.81

ChE_SM

0.7

0.81

0.79

ChE_TG

0.71

0.78

0.82

ChE_SM_TG

0.67

0.77

0.79

  1. Cer ceramides, SM sphingomyelins, ChE cholesteryl esters, DG diglycerides, TG triglycerides, PC phosphatidylcholines, LPC lyso-phosphatidylcholines, PE phosphatidylethanolamines, PI phosphatidylinositols, GLMnet elastic net penalization for the generalized linear model.
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