Table 1 Sociodemographic and clinical characteristics of the samples.
Neuroimaging sample | ||||
|---|---|---|---|---|
CUD (n = 75) (mean/%, SD/N) | Controls (n = 58) (mean/%, SD/N) | Statistics (df) | p | |
Sociodemographic | ||||
Age (years) | 32.86 (7.08) | 27.98 (7.12) | t(131) = −3.93 | >0.0001 |
Sex (male) | 49.3 (37) | 36.2 (21) | x2(1) = 2.29 | 0.130 |
Ethnicity (whites) | 44.6 (33) | 65.5 (36) | x2(3) = 5.95 | 0.114 |
Education (years) | 7.39 (2.75) | 11.33 (1.23) | W = 3768 | >0.0001 |
ASI-6 (standardized T scores) | ||||
Drugs | 52.08 (7.13) | - | ||
Family/child | 55.96 (10.01) | - | ||
Alcohol | 50.34 (8.85) | - | ||
Psychiatric status | 50.50 (7.74) | - | ||
Medical | 43.42 (8.11) | - | ||
Legal status | 49.89 (5.71) | - | ||
Employment | 38.94 (4.29) | - | ||
Family/social support | 50.94 (12.15) | - | ||
Family/social problems | 52.41 (8.96) | - | ||
SCID-I (SUD–current) | ||||
Cannabis | 29.3 (22) | - | ||
Snorted cocaine | 14.7 (11) | - | ||
Inhalant | 1.3 (1) | - | ||
Tobacco | 73.3 (55) | 5.1 (3) | x2(1) = 61.79 | >0.0001 |
Alcohol | 29.3 (22) | - | ||
Years of regular drug use—mean (SD) | ||||
Tobacco | 5.82 (9.10) | 3.90 (8.8) | W = 1102 | >0.0001 |
Alcohol | 6.64 (7.66) | 0.25 (0.94) | - | - |
Cannabis | 7.93 (7.63) | 0.10 (0.45) | - | - |
Cocaine | 8.18 (6.38) | 0 (0) | - | - |
Proteomics sample | ||||
CUD (n = 8) (mean/%, SD/N) | Controls (n = 12) (mean/%, SD/N) | Statistics (df) | p | |
Sociodemographic | ||||
Age (years) | 45.7 (9.72) | 51.7 (13.81) | W = 61.50 | 0.082 |
Sex (male) | 62.5 (5) | 83.3 (10) | x2(1) = 1.11 | 0.292 |
Ethnicity (whites) | 25 (2) | 58.3 (7) | Fisher exact | 0.197 |
Post-mortem intervals (hours) | 24.1 (8) | 29.4 (8.4) | W = 67 | 0.190 |
