Fig. 2: Longitudinal changes in microbial diversity in different groups. | Translational Psychiatry

Fig. 2: Longitudinal changes in microbial diversity in different groups.

From: Characterization of gut microbiome in mice model of depression with divergent response to escitalopram treatment

Fig. 2

Bacterial richness, here presented by Chao indices (a) and Ace indices (b) obtained at different time points from day 0 to week 4, NR and R group was higher than those in CON and CUMS groups in week 4. Data are presented with means and standard errors (*p < 0.05, Wilcoxon rank-sum test). Principal coordinate analysis (PCoA) plots based on unweighted UniFrac distances and the partial least squares-discriminant analysis (PLS-DA) showed distinct clusters on the OTU level among the four groups (c), and between the R and NR group (d), the bacterial communities of the R and NR group clustered separately. Statistical significance was determined by an ANOSIM with 999 permutations. The percentage of variation explained by principal co-ordinates is marked on the axes.

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